Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-(2-Ethyl-6-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 2-Ethyl-6-methylphenyl isothiocyanate | HCID 144188 | — |
| 반응물 | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-(2-Ethyl-6-methylphenyl)-1-methyl-2-thioxo-imidazolidin-4-one | HCID 85701470 | 60% |
반응 단계
The title compound was prepared by the procedure described in Example 1 using 8.9 g of 2-ethyl-6-methylphenyl-isothiocyanate, 7.68 g of sarcosine ethyl ester hydrochloride, 12.5 g of triethyl amine, and 250 mL of chloroform. Crystallization from diethyl ether afforded the title compound (7.45 g) as a peach solid, m.p. 106°-108° C. Anal. Calcd. for C13H16N2O S: C, 62.87; H, 6.49; N, 11.28. Found: C, 62.52; H, 6.61; N, 11.29. Mass spectrum (+ESI, [M+H]+) m/z 269/271.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05554607 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-a74ce4bf1f4e4ff389807055323a3b81 |
| 출처 메모 | uspto-grants-1996_09 |