Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 1-Ethyl-2-thioxo-3-(2,4,5-trimethylphenyl)-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 2,4,5-Trimethylphenyl isothiocyanate | HCID 140501 | — |
| 반응물 | N-Ethylglycine | HCID 316542 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 1-Ethyl-2-thioxo-3-(2,4,5-trimethylphenyl)-imidazolidin-4-one | HCID 11357492 | 58.4% |
반응 단계
The title compound was prepared by the procedure described in Example 16 using 17.7 g of 2,4,5-trimethylphenyl-isothiocyanate, 18.4 g of N-ethyl glycine, 20.2 g of triethyl amine, and 250 mL of chloroform. Crystallization from ethanol afforded the title compound (15.3g) as an off-white solid, m.p. 162°-164° C. Anal. Calcd. for. C14H18N2O S: C,64.09; H, 6.92; N, 10.68. Found: C, 64.21; H, 6.93; N, 10.80. Mass spectrum (EI, M.+) m/z 262.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05554607 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-9af578eb834c4bd482adb927dabf24cf |
| 출처 메모 | uspto-grants-1996_09 |