Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,5 Dibromotoluene → 1,4-Dibromo-2-(bromomethyl)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,5 Dibromotoluene | HCID 12006 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 촉매 | Benzyl Peroxide | HCID 11229634 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 1,4-Dibromo-2-(bromomethyl)benzene | HCID 5326038 | 55.7% |
반응 단계
To a solution of 75 g (0.3 mol) of 2,5-dibromotoluene in 1 L of carbon tetrachloride was added 58.73 g (0.33 mol) of NBS and 50 mg of benzyl peroxide, and the resulting mixture was refluxed with stirring for 24 h. The mixture was cooled, and concentrated in vacuo. The residue was crystallized from hot methanol and washed with hexane to afford 54.5 g (55.7%) of 2.5-dibromobenzyl bromide as a solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05554620 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-d1e95f67272f45da9c565ac04bac9e84 |
| 출처 메모 | uspto-grants-1996_09 |