Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Phenylethanol → 2-(3-(3-Phenethoxyphenyl)propyl)isoindoline-1,3-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Phenylethanol | HCID 6054 | — |
| 반응물 | 2-[3-(3-Hydroxyphenyl)propyl]isoindole-1,3-dione | HCID 58027542 | — |
| 생성물 | 2-(3-(3-Phenethoxyphenyl)propyl)isoindoline-1,3-dione | HCID 67316019 | — |
반응 단계
Mitsunobu reaction of phenol 58 with phenethyl alcohol gave 2-(3-(3-phenethoxyphenyl)propyl)isoindoline-1,3-dione as yellow oil. Yield (0.360 g, 30%): 1H NMR (400 MHz, CDCl3) δ 7.77-7.81 (m, 2H), 7.66-7.71 (m, 2H), 7.22-7.34 (m, 6H), 6.71-6.78 (m, 2H), 6.65 (dd, J=7.2, 2.0 Hz, 1H), 3.87 (t, J=6.8, 2H), 3.74 (t, J=7.2 Hz, 2H), 2.88 (t, J=6.4 Hz, 2H), 2.65 (t, J=7.2 Hz, 2H), 1.98-2.06 (m, 2H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829244B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-5a3fe2eb9d0d474db508663357c14e14 |
| 출처 메모 | uspto-grants-2014_09 |