Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen chloride-ethyl acetate → 1-{3-[2-(1-Benzothiophen-6-yl)ethoxy]propyl}-3-azetidinol hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| 반응물 | 1-(3-(2-(1-Benzothiophene-6-yl)ethoxy)propyl)-3-azetidinol | HCID 23545564 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 1-{3-[2-(1-Benzothiophen-6-yl)ethoxy]propyl}-3-azetidinol hydrochloride | HCID 66588413 | — |
반응 단계
In 3.0 mL of ethyl acetate was dissolved 0.28 g of 1-{3-[2-(1-benzothiophen-6-yl)ethoxy]propyl}-3-azetidinol, and to the solution was added 0.35 mL of a 3.25 mol/L dried hydrogen chloride-ethyl acetate solution, after which the resulting mixture was stirred at room temperature for 1 hour. Then, the solvent was distilled off under reduced pressure to obtain 0.30 g of 1-{3-[2-(1-benzothiophen-6-yl)ethoxy]propyl}-3-azetidinol hydrochloride as a light-yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087594B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-8299922f87304667a70416c850fe5f40 |
| 출처 메모 | uspto-grants-2006_08 |