Water → HCID 178522838, 화합물

반응식

Cl.[NH:2]1[CH:6]=[C:5]([CH2:7][CH2:8][CH2:9][OH:10])[N:4]=[CH:3]1.C([N:13]([CH2:16][CH3:17])[CH2:14]C)C.[OH2:18]>>[CH2:16]([NH:13][C:14](=[O:18])[O:10][CH2:9][CH2:8][CH2:7][C:5]1[N:4]=[CH:3][NH:2][CH:6]=1)[C:17]1[CH:9]=[CH:8][CH:7]=[CH:5][CH:6]=1

참가 물질

반응물 3

HCID 962Water

HCID 8471Triethylamine

HCID 178479684HCID 178479684, 화합물

생성물 1

HCID 178522838HCID 178522838, 화합물

실험 절차

The preparation is carried out as in Example 23 with 3-(1H-imidazol-4-yl)propanol hydrochloride and 5 mmol of triethylamine. The residual oil is taken up in a small amount of water. The title compound is crystallized in the hydrogenmaleate form from ethanol/diethyl ether.