Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 4-Methoxy-3-(3-methoxypropoxy)benzenemethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Hydroxy-4-methoxybenzyl alcohol | HCID 78089 | — |
| 반응물 | 1-Bromo-3-methoxypropane | HCID 524551 | — |
| 반응물 | Ethyl acetate hexane | HCID 21226206 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 4-Methoxy-3-(3-methoxypropoxy)benzenemethanol | HCID 45108163 | — |
반응 단계
7.7 g of 3-hydroxy-4-methoxy-benzyl alcohol, 10.35 g of potassium carbonate and 12.1 g of 1-bromo-3-methoxy-propane are stirred under reflux in 150 ml of acetone for 3 days. After evaporation of the solvent, water is added to the residue and extraction is carried out with ethyl acetate. After evaporation of the solvent the title compound is obtained from the organic extracts by means of FC (240 g of silica gel, dichloromethane/methanol=96:4): Rf (ethyl acetate/hexane=2:1)=0.31.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05559111 |
| 출처 데이터셋 | uspto-grants-1996_09 |
| ORD ID | ord-90987c5053f4457cbdcb4e6353323a94 |
| 출처 메모 | uspto-grants-1996_09 |