Methyl formate → 1-Piperazinecarboxaldehyde, 2-(1H-indol-3-yl)-3-oxo-

HRID 745237노트

반응식

HRID 745237 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]2[NH:15][CH2:14][CH2:13][NH:12][C:11]2=[O:16])=[CH:2]1.[CH3:17][O:18]C=O>>[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]2[N:15]([CH:17]=[O:18])[CH2:14][CH2:13][NH:12][C:11]2=[O:16])=[CH:2]1

참가 물질

3

반응물 2

HCID 7865Methyl formateHCID 131206953-(1H-Indol-3-yl)-2-piperazinone

생성물 1

HCID 30700241-Piperazinecarboxaldehyde, 2-(1H-indol-3-yl)-3-oxo-

실험 절차

21.5 g (0.1 mol) of 3-(3-indolyl)-piperazin-2-one (Example 30) are formylated with methylformate, as described in Example 5.

출처 및 근거

ORD 기록
ord-b21fb15113c84d0bac1464c888437a17
출처 데이터셋
uspto-grants-1986_07
특허 번호
US04598079

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