Triethylamine → HCID 58386575, 화합물

참여 물질

역할	이름	HCID	투입량
반응물	Triethylamine	HCID 8471	—
반응물	5-Nitroindoline	HCID 36219	—
반응물	O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate	HCID 2733207	—
반응물	6-[4-(2-Oxo-2,3-dihydroimidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]pyrimidine-4-carboxylic acid	HCID 58386696	—
용매	Water	HCID 962	—
용매	Dimethylformamide	HCID 6228	—
생성물	HCID 58386575	HCID 58386575	—

반응 단계

150 mg (0.47 mmol) TBTU were added to 150 mg (0.44 mmol) 6-[4-(2-oxo-2,3-dihydro-imidazo[4,5-b]pyridin-1-yl)-piperidin-1-yl]-pyrimidine-4-carboxylic acid, 75 mg (0.46 mmol) 5-nitro-2,3-dihydro-1H-indole, 100 μL and (0.712 mmol) triethylamine in 1.5 mL DMF and the mixture was stirred overnight at RT. The reaction mixture was poured onto 30 mL water. The precipitated product was suction filtered and dried at 50° C. in the CAD.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08829006B2
출처 데이터셋	uspto-grants-2014_09
ORD ID	ord-82f55e6c994141e0a18f1092baf0e473
출처 메모	uspto-grants-2014_09