HCID 908572, 화합물 → HCID 1790984, 화합물

HRID 745306노트

반응식

HRID 745306 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[C:9]1=[CH:15][C:16](=[O:20])[NH:17][C:18](=[O:19])[N:8]1[CH2:7][CH2:6]2.F[B-](F)(F)F.[CH2:26]([O+](CC)CC)[CH3:27]>ClCCl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[C:9]1=[CH:15][C:16]([O:20][CH2:26][CH3:27])=[N:17][C:18](=[O:19])[N:8]1[CH2:7][CH2:6]2

참가 물질

4

반응물 2

HCID 908572HCID 908572, 화합물HCID 2723982Triethyloxonium tetrafluoroborate

생성물 1

HCID 1790984HCID 1790984, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

A mixture of 3.0 g of 9,10-dimethoxy-3,4,6,7-tetrahydro-2H-pyrimido(6,1-a)isoquinolin-2,4-dione and 15.0 g of triethyloxonium fluoroborate in 100 ml of dichloromethane is stirred overnight. The reaction mixture is washed with a solution of sodium carbonate. The organic layer is separated and dried over anhydrous sodium sulfate. Evaporation of the solvent gives the title compound, yield 1.8 g.

후처리

  1. washThe reaction mixture is washed with a solution of sodium carbonate
  2. customThe organic layer is separated
  3. dry with materialdried over anhydrous sodium sulfate
  4. customEvaporation of the solvent

출처 및 근거

ORD 기록
ord-9735da0f61c2473cac24861bfa5ddc0a
출처 데이터셋
uspto-grants-1986_07
특허 번호
US04598148

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