Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 2-Methylene-3-quinuclidone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Methylene-3-quinuclidinone dihydrate hydrochloride | HCID 21954275 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-Methylene-3-quinuclidone | HCID 322973 | — |
반응 단계
Suspend 95.4 g (0.455 mole) 2-methylene-3-quinuclidinone dihydrate hydrochloride in a solution of 255 g (1.85 moles) anhydrous potassium carbonate dissolved in 350 ml H2O. When the suspension clears add 500 ml methylene chloride and mix the 2-phase system overnight using a mechanical stirrer. Separate the layers and dry the methylene chloride layer over potassium carbonate. Remove the solvents in vacuo to obtain the title compound. Repeat the extraction until most of the product is collected.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04599344 |
| 출처 데이터셋 | uspto-grants-1986_07 |
| ORD ID | ord-8487bf1433834c318e8cfa3a4af4c32e |
| 출처 메모 | uspto-grants-1986_07 |