Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylsilane → methyl (4-nitro-2,3-dihydro-1H-indol-3-yl)-acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylsilane | HCID 12052 | — |
| 반응물 | Methyl (4-nitro-1H-indol-3-yl)(oxo)acetate | HCID 10243717 | — |
| 용매 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | methyl (4-nitro-2,3-dihydro-1H-indol-3-yl)-acetate | HCID 10243182 | — |
반응 단계
Under an argon atmosphere 16 mL (0.10 mmol) triethylsilane were slowly added dropwise to 2.3 g (9.3 mmol) methyl (4-nitro-1H-indol-3-yl)-oxo-acetate in 18 mL trifluoroacetic acid while cooling with ice. Then the mixture was stirred for a further 3 h at RT and evaporated down. The residue was dried and then triturated with diisopropylether, suction filtered and dried in the air.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08829006B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-4dc15c7d857a4497b86d2906e813aebc |
| 출처 메모 | uspto-grants-2014_09 |