Hexamethylenediamine → N-(6-aminohexyl)-aminomethanephosphonic acid monohydrate
반응식
Cl[CH2:2][P:3]([OH:6])(=[O:5])[OH:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH2:14]>O>[OH2:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][NH:14][CH2:2][P:3]([OH:6])(=[O:5])[OH:4]참가 물질
4
실험 절차
Chloromethanephosphonic acid (6.5 g, 49.8 mmoles) and 1.6-diaminohexane (34.8 g, 300 mmoles) were dissolved in water (130 cm3) and heated under reflux for 20 hours. The water was removed and ethanol (250 cm3) was added to the solid residue. The phosphonic acid was filtered off and dried. The crude yield was 10.4 g (92%). A sample was purified by recrystallization from water/ethanol to give N-(6-aminohexyl)-aminomethanephosphonic acid monohydrate as a fine white crystalline solid having a melting point of 235° C.
후처리
- temperatureheated
- temperatureunder reflux for 20 hours
- customThe water was removed
- additionethanol (250 cm3) was added to the solid residue
- filtrationThe phosphonic acid was filtered off
- customdried
- customA sample was purified by recrystallization from water/ethanol
출처 및 근거
- ORD 기록
- ord-1f74a984e1044d61a0a328a35fa3b720
- 출처 데이터셋
- uspto-grants-1986_07
- 특허 번호
- US04600429
반응 노트
불러오는 중…