Methanol → 2-Cyclopropyl-4,6-dimethoxy-1,3,5-triazine

반응식

[CH3:1][O-:2].[Na+].[CH:4]1([C:7]2[N:12]=[C:11](C(Cl)(Cl)Cl)[N:10]=[C:9](C(Cl)(Cl)Cl)[N:8]=2)[CH2:6][CH2:5]1.[CH3:21][OH:22]>>[CH:4]1([C:7]2[N:12]=[C:11]([O:2][CH3:1])[N:10]=[C:9]([O:22][CH3:21])[N:8]=2)[CH2:6][CH2:5]1

참가 물질

반응물 3

HCID 887Methanol

HCID 10942334Sodium Methoxide

HCID 201996132-Cyclopropyl-4,6-bis-trichloromethyl-1,3,5-triazine

생성물 1

HCID 201996162-Cyclopropyl-4,6-dimethoxy-1,3,5-triazine

실험 절차

8.1 g of sodium methylate are added to a solution of 71.2 g of 2-cyclopropyl-4,6-bis-(trichloromethyl)-1,3,5-triazine in 200 ml of methanol, and stirring is maintained for 5 hours at room temperature. The solution is then evaporated to dryness, and the residue is stirred up with 200 ml of ether. The resulting suspension is filtered and the filtrate is concentrated by evaporation. The residue crystallises, and is recrystallised from ether/hexane. The yield is 35.7 g of the above triazine, m.p. 68°-70° C.