HCID 13655641, 화합물 → HCID 13655651, 화합물

HRID 745747노트

반응식

HRID 745747 반응식
[Br:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([CH2:8][C:9](=[CH2:13])[C:10]([OH:12])=[O:11])=[O:7])=[CH:4][CH:3]=1.C(O)(=S)C.[C:20]([OH:24])(=[S:23])[CH2:21][CH3:22]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([CH2:8][CH:9]([CH2:13][S:23][C:20](=[O:24])[CH2:21][CH3:22])[C:10]([OH:12])=[O:11])=[O:7])=[CH:14][CH:15]=1

참가 물질

4

반응물 3

HCID 13655641HCID 13655641, 화합물HCID 178418634HCID 178418634, 화합물HCID 178460587HCID 178460587, 화합물

생성물 1

HCID 13655651HCID 13655651, 화합물수율 71%

실험 절차

Following the procedure of Example 1 using 26.9 g of 3-(4-bromobenzoyl)-2-methylenepropionic acid and 10 ml of thiopropionic acid in place of 19.0 g of 3-benzoyl-2-methylenepropionic acid and 8.0 ml of thioacetic acid, respectively, there was obtained 25.5 g (yield: 71%) of 3-(4-bromobenzoyl)-2-propionylthiomethylpropionic acid as crystals.

출처 및 근거

ORD 기록
ord-f35767e794134c8e91efce898634484c
출처 데이터셋
uspto-grants-1986_07
특허 번호
US04600540

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