Methyl 4-(3-amino-1H-pyrazol-5-yl)benzoate → HCID 178497538, 화합물
반응식
NC1C=CNN=1.O/[CH:8]=[C:9]1\[C:10](=[O:18])[NH:11][C:12]2[C:17]\1=[CH:16][CH:15]=[CH:14][CH:13]=2.[CH3:19][O:20][C:21](=[O:34])[C:22]1[CH:27]=[CH:26][C:25]([C:28]2[NH:29][N:30]=[C:31]([NH2:33])[CH:32]=2)=[CH:24][CH:23]=1>O1CCCC1>[CH3:19][O:20][C:21](=[O:34])[C:22]1[CH:23]=[CH:24][C:25]([C:28]2[NH:29][N:30]=[C:31]([NH:33][CH:8]=[C:9]3[C:17]4[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=4)[NH:11][C:10]3=[O:18])[CH:32]=2)=[CH:26][CH:27]=1참가 물질
5
실험 절차
The named compound is prepared by substituting 4-(5-amino-2H-pyrazol-3-yl)-benzoic acid methyl ester for 3-aminopyrazole in the reaction of Example 1. Specifically, E & Z-3-[(hydroxy)-methylene]-1,3-dihydro-indol-2-one (0.100 gms.) is reacted with 0.2847 gms. of 4-(5-amino-2H-pyrazol-3-yl)-benzoic acid methyl ester by refluxing in tetrahydrofuran (2.5 mL).