Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl chloroformate → Ethyl 3-methyl-4-oxopiperidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl chloroformate | HCID 10928 | — |
| 반응물 | 1-Benzyl-3-methyl-4-piperidone | HCID 560965 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | Ethyl 3-methyl-4-oxopiperidine-1-carboxylate | HCID 15075657 | — |
반응 단계
Ethyl chloroformate (3.0 g, 26.7 mmol) was added to a stirred solution of 1-benzyl-3-methyl-4-piperidinone (2.0 g, 9.85 mmol) in benzene (30 ml) at ambient temperature. The obtained reaction mixture was refluxed with stirring for 6 hr and concentrated to dryness to give 1-carbethoxy-3-methyl-4-piperidone as oil. Yield 1.4 g (77%), C9H15NO3, m/z 186 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07393957B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-bfe13196bddf4f0f97ac0ec455d56a67 |
| 출처 메모 | uspto-grants-2008_07 |