Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethylamine → N,N-diethyl-4-iodobenzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethylamine | HCID 8021 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 4-Iodobenzoyl chloride | HCID 74373 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N,N-diethyl-4-iodobenzamide | HCID 875218 | — |
반응 단계
To a mixture of 4-iodo-benzoyl chloride (75 g) in 500 mL CH2Cl2 was added a mixture of Et3N (50 mL) and Et2NH (100 mL) at 0° C. After the addition, the resulting reaction mixture was warmed up to room temperature in 1 hr and was then washed with saturated ammonium chloride. The organic extract was dried (Na2SO4), filtered and concentrated. Residue was recrystallized from hot hexanes to give 80 g of INTERMEDIATE 5.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07396834B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-28b78c804afd448ea22a9636a4b3cf3b |
| 출처 메모 | uspto-grants-2008_07 |