Norbornadiene → HCID 59749439, 화합물
반응식
[N:1]([CH2:4][CH:5]1[O:9][N:8]=[C:7]([C:10]2[CH:15]=[CH:14][C:13]([Br:16])=[CH:12][CH:11]=2)[CH2:6]1)=[N+:2]=[N-:3].[CH:17]12CC(C=C1)C=[CH:18]2>O1CCOCC1>[Br:16][C:13]1[CH:14]=[CH:15][C:10]([C:7]2[CH2:6][CH:5]([CH2:4][N:1]3[CH:18]=[CH:17][N:3]=[N:2]3)[O:9][N:8]=2)=[CH:11][CH:12]=1참가 물질
4
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- 온도
- 100 °C
실험 절차
5-Azidomethyl-3-(4-bromo-phenyl)-4,5-dihydro-isoxazol (12.3 g, 43.6 mmol) and bicyclo[2.2.1]hepta-2,5-diene (23.6 ml, 218.1 mmol) were added to dioxane (200 ml), heated to 100° C. and stirred for six hours. The reaction mixture was concentrated in vacuo followed by addition of ethyl ether (200 ml). The precipitate was collected and washed with ethyl ether (3×20 ml) and dried under nitrogen to give the desired product (8.8 g).
후처리
- concentrationThe reaction mixture was concentrated in vacuo
- additionfollowed by addition of ethyl ether (200 ml)
- customThe precipitate was collected
- washwashed with ethyl ether (3×20 ml)
- customdried under nitrogen
출처 및 근거
- ORD 기록
- ord-3e50b0ba231a47a58d07fc81d02524df
- 출처 데이터셋
- uspto-grants-2008_07
- 특허 번호
- US07396847B2
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