Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 2-(4-Phenyl-2-pyridyl)-4H-1,3-benzothiazine-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Benzoic acid, 2-mercapto-, methyl ester | HCID 21009 | — |
| 반응물 | 4-Phenyl-2-pyridinecarbonitrile | HCID 87758 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-(4-Phenyl-2-pyridyl)-4H-1,3-benzothiazine-4-one | HCID 59750104 | 53% |
반응 단계
A mixture of methyl thiosalicylate (1.00 g, 5.9 mmol), 2-cyano-4-phenylpyridine (1.10 g, 5.9 mmol), triethylamine (1.30 ml, 9.0 mmol) and toluene (2.5 ml) was refluxed for 20 hrs. After cooling, the precipitated crystals were collected by filtration and recrystallized from ethanol to give the titled compound (0.99 g, 53%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07399759B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-6bfd023bf67c4242aeebaa9e89b02d32 |
| 출처 메모 | uspto-grants-2008_07 |