1-Hydroxybenzotriazole → 3-((2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-ylamino)piperidin-1-yl)-3-methylbutan-1-one

참여 물질

역할	이름	HCID	투입량
반응물	1-Hydroxybenzotriazole	HCID 75771	—
반응물	1-Methylcyclopropanecarboxylic acid	HCID 81326	—
반응물	Diisopropylethylamine	HCID 81531	—
반응물	1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride	HCID 2723939	—
반응물	dichloromethane N,N-dimethylformamide	HCID 22350042	—
생성물	3-((2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-ylamino)piperidin-1-yl)-3-methylbutan-1-one	HCID 131731863	—

1-methylcyclopropane-1-carboxylic acid, EDAC-HCl, HOBt, iPr2NEt, CH2Cl2/DMF.