Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → (R)-N-(2-Azido-1-benzylethyl)-4-hydroxy-1-methyl-1H-indole-2-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | (R)-2-azido-1-benzylethylamine | HCID 14802497 | — |
| 반응물 | 3-Hydroxy-1-methyl-1H-indole-2-carboxylic acid | HCID 54711425 | — |
| 생성물 | (R)-N-(2-Azido-1-benzylethyl)-4-hydroxy-1-methyl-1H-indole-2-carboxamide | HCID 86601455 | — |
반응 단계
From (R)-2-azido-1-benzylethylamine (prepared as described by Horwell, et al., J. Med. Chem., 1991, 404-414) and 4 hydroxy-1-methyl-1H-indole-2-carboxylic acid the title compound was prepared by a method analogous to that described in Example 13. MS ES (M++H)=350; [α]D=+94.8° (MeOH, C=1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07402604B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-81e0566dba6b411db778eb9a23341747 |
| 출처 메모 | uspto-grants-2008_07 |