Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cesium carbonate → 2-(2,2,3,3,3-Pentafluoropropyl)-2-(4-(trifluoromethyl)benzyl)malononitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | 2,2,3,3,3-Pentafluoropropyl trifluoromethanesulfonate | HCID 2776019 | — |
| 반응물 | (4-(Trifluoromethyl)benzyl)malononitrile | HCID 10656743 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(2,2,3,3,3-Pentafluoropropyl)-2-(4-(trifluoromethyl)benzyl)malononitrile | HCID 22235067 | 34% |
반응 단계
Using 0.50 g of (4-(trifluoromethyl)benzyl)malononitrile, 5 ml of N,N-dimethylformamide, 363 mg of cesium carbonate, and 0.63 g of 2,2,3,3,3-pentafluoropropyl trifluoromethanesulfonate, and according to the process described in the Production Example 1, there was obtained 0.20 g of 2-(2,2,3,3,3-pentafluoropropyl)-2-(4-(trifluoromethyl)benzyl)malononitrile (the present compound (76)).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07402691B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-d98cfaa7544d4cb78377b0370f214263 |
| 출처 메모 | uspto-grants-2008_07 |