Methyl 5-(tert-butoxycarbonylamino)-1-methylcyclohex-3-enecarboxylate → HCID 67285117, 화합물

HRID 74998노트

반응식

HRID 74998 반응식
[C:1]([O:5][C:6]([NH:8][CH:9]1[CH2:14][C:13]([CH3:19])([C:15]([O:17][CH3:18])=[O:16])[CH2:12][CH:11]=[CH:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>CO.[Pd]>[C:1]([O:5][C:6]([NH:8][CH:9]1[CH2:14][C:13]([CH3:19])([C:15]([O:17][CH3:18])=[O:16])[CH2:12][CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 67285544Methyl 5-(tert-butoxycarbonylamino)-1-methylcyclohex-3-enecarboxylate

생성물 1

HCID 67285117HCID 67285117, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

Methyl 5-(tert-butoxycarbonylamino)-1-methylcyclohex-3-enecarboxylate, 52f, (5.59 g, 20.75 mmol) was dissolved in 100 mL of MeOH. To the stirred solution was added 5% palladium on carbon (1.11 g, 10.38 mmol) and the reaction was stirred under a hydrogen balloon for 2 days. The reaction was filtered through celite, and the filtrate was concentrated in vacuo and used without further purification.

후처리

  1. filtrationThe reaction was filtered through celite
  2. concentrationthe filtrate was concentrated in vacuo
  3. customused without further purification

출처 및 근거

ORD 기록
ord-a7a8e5b9180c4b33bb94616ad6c821cd
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08829007B2

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