2-Benzoyl-4-bromobenzoic acid → HCID 69157217, 화합물

반응식

Cl.[CH3:2][O:3][C:4](=[O:19])[C:5]1[CH:10]=[CH:9][C:8]([CH2:11][NH:12][CH2:13][CH:14]([OH:18])[CH2:15][CH2:16][CH3:17])=[CH:7][CH:6]=1.[C:20]([C:28]1[CH:36]=[C:35]([Br:37])[CH:34]=[CH:33][C:29]=1[C:30](O)=[O:31])(=O)[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[CH3:2][O:3][C:4](=[O:19])[C:5]1[CH:6]=[CH:7][C:8]([CH2:11][N:12]2[C:13]([C:14](=[O:18])[CH2:15][CH2:16][CH3:17])=[C:20]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[C:28]3[C:29](=[CH:33][CH:34]=[C:35]([Br:37])[CH:36]=3)[C:30]2=[O:31])=[CH:9][CH:10]=1

참가 물질

반응물 2

HCID 3467342-Benzoyl-4-bromobenzoic acid

HCID 69156613HCID 69156613, 화합물

생성물 1

HCID 69157217HCID 69157217, 화합물

실험 절차

In the same manner as in Example 458, Step 2, the title compound was synthesized from 4-[(2-hydroxypentylamino)methyl]benzoic acid methyl ester hydrochloride and 2-benzoyl-4-bromobenzoic acid.

출처 및 근거

ORD 기록: ord-d49713e10a194c75839b555dee2a9447
출처 데이터셋: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07402595B2

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