Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl (1-cyanoethyl)phosphonate → (S)-N-{3-[4-(4-(1-cyanoethylidene)-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl (1-cyanoethyl)phosphonate | HCID 282103 | — |
| 반응물 | (S)-{3-[4-(4-oxo-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine | HCID 69315308 | — |
| 생성물 | (S)-N-{3-[4-(4-(1-cyanoethylidene)-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine | HCID 69315435 | 74% |
반응 단계
The compound was prepared by following the procedure of Example-1 and by using (S)-{3-[4-(4-oxo-piperidin-1-yl)-3-fluorophenyl]-2-oxo-oxazolidin-5-ylmethyl}-amine and diethyl-(1-cyanoethyl)-phosphonate in 74% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07405228B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-6f684710c0a748bfb0eae79346601052 |
| 출처 메모 | uspto-grants-2008_07 |