2,5-Difluorobenzoyl chloride → HCID 16770181, 화합물

HRID 75112

반응식

HRID 75112 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:12]=[CH:13][C:14]=1F)[C:5]([NH:7][CH2:8][C:9]([OH:11])=[O:10])=[O:6].[F:16]C1C=CC(F)=CC=1C(Cl)=O>>[F:16][C:12]1[CH:13]=[CH:14][C:2]([F:1])=[CH:3][C:4]=1[C:5]([NH:7][CH2:8][C:9]([OH:11])=[O:10])=[O:6]

참가 물질

3

반응물 2

HCID 5880822,5-Difluorobenzoyl chlorideHCID 7051412-[(3,4-Difluorophenyl)formamido]acetic acid

생성물 1

HCID 16770181HCID 16770181, 화합물

실험 절차

2-(2,5-difluorobenzamido)acetic acid was prepared in the same manner as 2-(3,4-difluorobenzamido)acetic acid described above, except that 2,5-difluorobenzoyl chloride was used in place of 3,4-difluorobenzoyl chloride. LCMS (+ESI) m/z 216.2 [M+H]+. 1H-NMR (dmso d6) δ 12.69 (br s, 1H), 8.66 (bdd, 1H), 7.55-7.30 (m, 3H), 7.75 (m, 1H), 3.93 (d, 2H).

출처 및 근거

ORD 기록
ord-0895c27509b0474db7b62f6f98789ba8
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08835422B2

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