Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Iodo-4-(trifluoromethoxy)benzene → 2-(1H-Indol-6-yl)-N-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Iodo-4-(trifluoromethoxy)benzene | HCID 2777294 | — |
| 반응물 | 2-(1H-Indol-6-yl)-N-prop-2-ynyl-acetamide | HCID 86095505 | — |
| 생성물 | 2-(1H-Indol-6-yl)-N-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-acetamide | HCID 68825664 | — |
반응 단계
In analogy to the procedure described for example 8 a], 2-(1H-indol-6-yl)-N-prop-2-ynyl-acetamide was reacted with 4-(trifluoromethoxy)-iodobenzene in the presence of PdCl2(Ph3P)2 and cuprous iodide to give the title compound as colorless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07405236B2 |
| 출처 데이터셋 | uspto-grants-2008_07 |
| ORD ID | ord-2d278a71bb944401bfba164c31f4be3d |
| 출처 메모 | uspto-grants-2008_07 |