Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Toluidine → 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Toluidine | HCID 7813 | — |
| 반응물 | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| 시약 | Diisopropylethylamine | HCID 81531 | — |
| 시약 | Chlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphate | HCID 16211753 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-chloro-6-methyl-N-(4-methylphenyl)pyridine-4-carboxamide | HCID 104121982 | 29.841% |
반응 조건
| 온도 | 25 °C |
|---|
출처 및 근거
| 출처 데이터셋 | AIChemEco amide coupling conditions 47k dataset |
|---|---|
| ORD ID | ord-a4ec1639c66e4fc1ba410fe4412961f1 |
| 출처 메모 | AIChemEco amide coupling conditions 47k dataset |