Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cyclobutanecarbonyl chloride → N-[1-(3-cyclopropyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]cyclobutanecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cyclobutanecarbonyl chloride | HCID 78705 | — |
| 반응물 | 6-(1-Aminopropyl)-3-cyclopropyl-1,2,4-triazin-5(4h)-one | HCID 135594071 | — |
| 생성물 | N-[1-(3-cyclopropyl-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)propyl]cyclobutanecarboxamide | HCID 135752531 | — |
반응 단계
In analogy to the procedure for Example 36A, 250 mg (1.29 mmol) 6-(1-aminopropyl)-3-cyclopropyl-1,2,4-triazin-5(4H)-one, 150 mg (1.29 mmol) cyclobutanecarbonyl chloride and proportionate amounts of the other reagents are used. The crude product is used in the next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07087605B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-e8a991ceb0764091bbad87e8571af243 |
| 출처 메모 | uspto-grants-2006_08 |