Cyclopentanecarbonyl chloride → N-{1-[3-(3-Nitrophenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}cyclopentanecarboxamide

HRID 7546

반응식

HRID 7546 반응식
[NH2:1][CH:2]([C:5]1[C:6](=[O:20])[NH:7][C:8]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N+:17]([O-:19])=[O:18])[CH:12]=2)=[N:9][N:10]=1)[CH2:3][CH3:4].[CH:21]1([C:26](Cl)=[O:27])[CH2:25][CH2:24][CH2:23][CH2:22]1>>[N+:17]([C:13]1[CH:12]=[C:11]([C:8]2[NH:7][C:6](=[O:20])[C:5]([CH:2]([NH:1][C:26]([CH:21]3[CH2:25][CH2:24][CH2:23][CH2:22]3)=[O:27])[CH2:3][CH3:4])=[N:10][N:9]=2)[CH:16]=[CH:15][CH:14]=1)([O-:19])=[O:18]

참가 물질

3

반응물 2

HCID 78284Cyclopentanecarbonyl chlorideHCID 1355941026-(1-aminopropyl)-3-(3-nitrophenyl)-1,2,4-triazin-5(4H)-one

생성물 1

HCID 135752527N-{1-[3-(3-Nitrophenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]propyl}cyclopentanecarboxamide

실험 절차

In analogy to the procedure for Example 36A, 3.0 g (10.9 mmol) 6-(1-aminopropyl)-3-(3-nitrophenyl)-1,2,4-triazin-5(4H)-one, 2.2 g (16.3 mmol) cyclopentanecarbonyl chloride and proportionate amounts of the other reagents are used.

출처 및 근거

ORD 기록
ord-fea17c083a1e486d9dd4e00e7e5ed49c
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07087605B2

연결된 노트

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