4-Chlorobenzaldehyde → N-((1SR,4SR,7RS)-2-(4-chlorobenzyl)-2-azabicyclo[2.2.1]heptan-7-yl)-1H-indazol-5-amine

HRID 75691노트

반응식

[CH:1]12[CH:7]([NH:8][C:9]3[CH:10]=[C:11]4[C:15](=[CH:16][CH:17]=3)[N:14](C(=O)C(C)(C)C)[N:13]=[CH:12]4)[CH:4]([CH2:5][CH2:6]1)[CH2:3][NH:2]2.[Cl:24][C:25]1[CH:32]=[CH:31][C:28]([CH:29]=O)=[CH:27][CH:26]=1>>[Cl:24][C:25]1[CH:32]=[CH:31][C:28]([CH2:29][N:2]2[CH2:3][CH:4]3[CH:7]([NH:8][C:9]4[CH:10]=[C:11]5[C:15](=[CH:16][CH:17]=4)[NH:14][N:13]=[CH:12]5)[CH:1]2[CH2:6][CH2:5]3)=[CH:27][CH:26]=1

참가 물질

반응물 2

HCID 77264-Chlorobenzaldehyde

HCID 58306368HCID 58306368, 화합물

생성물 1

HCID 53246935N-((1SR,4SR,7RS)-2-(4-chlorobenzyl)-2-azabicyclo[2.2.1]heptan-7-yl)-1H-indazol-5-amine

실험 절차

Reaction of Intermediate 14 with 4-chlorobenzaldehyde affords the title compound.

출처 및 근거

ORD 기록: ord-de586824c42a425a94ced7229dc91b5f
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08835457B2

반응 노트

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