Cesium carbonate → N-(1-(4-((4-(Pyrimidin-5-yloxy)phenyl)ethynyl)phenyl)propan-2-yl)acetamide
반응식
I[C:2]1[CH:3]=[N:4][CH:5]=[N:6][CH:7]=1.[OH:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]#[C:16][C:17]2[CH:22]=[CH:21][C:20]([CH2:23][CH:24]([NH:26][C:27](=[O:29])[CH3:28])[CH3:25])=[CH:19][CH:18]=2)=[CH:11][CH:10]=1.Cl.CN(C)CC(O)=O.C([O-])([O-])=O.[Cs+].[Cs+]>[Cu]I.O1CCOCC1>[N:4]1[CH:3]=[C:2]([O:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]#[C:16][C:17]3[CH:22]=[CH:21][C:20]([CH2:23][CH:24]([NH:26][C:27](=[O:29])[CH3:28])[CH3:25])=[CH:19][CH:18]=3)=[CH:11][CH:10]=2)[CH:7]=[N:6][CH:5]=1
