(S)-1-Boc-3-methylpiperazine → HCID 68430969, 화합물

반응식

C(OC(N1CCN[C@@H](C)C1)=O)(C)(C)C.[ClH:15].[CH3:16][CH:17]1[CH2:22][NH:21][CH2:20][CH:19](C)[N:18]1[C:24]1[N:29]=[CH:28][CH:27]=[CH:26][N:25]=1>>[ClH:15].[CH3:16][C@@H:17]1[N:18]([C:24]2[N:25]=[CH:26][CH:27]=[CH:28][N:29]=2)[CH2:19][CH2:20][NH:21][CH2:22]1

참가 물질

반응물 2

HCID 7023035(S)-1-Boc-3-methylpiperazine

HCID 684321412-(2,6-Dimethylpiperazin-1-yl)pyrimidine hydrochloride

생성물 1

HCID 68430969HCID 68430969, 화합물

실험 절차

Using (3S)-1-tert-butyloxycarbonyl-3-methylpiperazine, reactions similar to those in Example 1 (2), (3) were successively performed to give (3S)-3-methyl-4-pyrimidin-2-ylpiperazine hydrochloride, then reactions similar to those in Example 1 (4) were successively performed to give the title compound (216 mg).

출처 및 근거

ORD 기록: ord-addd1c5420634d158f029448587dd06a
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08835631B2

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