참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonium Hydroxide | HCID 14923 | — |
| 반응물 | D-tert-leucine | HCID 6950340 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-Amino-3,3-dimethylbutanoic acid | HCID 306131 | 92% |
반응 단계
Ammonium hydroxide (50 mL, 30%) solution was placed in an autoclave and D-tert-leucine (5 g) was added. Autoclave was closed and the contents were heated to 85° C. under stirring for 12 hours. After cooling the solution was transferred and concentrated under vacuum at 55° C. The solid residue obtained was stirred with acetone (20 mL), filtered and dried to obtain DL-tert-leucine (4.6 g, 92% yield, L-isomer: 42%, D-isomer: 58%)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08835676B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_09 |
|---|
| ORD ID | ord-d453e83ed0824a199660d4e90a242ef9 |
|---|
| 출처 메모 | uspto-grants-2014_09 |
|---|
