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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 7801생성일: 2026년 10월 23일

Cyclohexene → 5-[3-(4-Aminophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazole

https://huagongshe.com/ko/reaction/7801

반응식

참여 물질

역할이름HCID투입량
반응물CyclohexeneHCID 8079—
반응물5-[3-(4-Nitrophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazoleHCID 21992365—
촉매HCID 178418390HCID 178418390—
용매MethanolHCID 887—
생성물5-[3-(4-Aminophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazoleHCID 21992411103%

반응 단계

45 mg of 5-[3-(4-nitrophenyl)propyl]-3-(4-fluorophenyl)-1-methyl-4-(4-pyridyl)pyrazole was dissolved in 6 ml of methanol, followed by the addition of 2 ml of cyclohexene. Then, 45 mg of 10% palladium-carbon was added thereto, followed by heating under reflux for 2 hours. After the reaction mixture was filtered, the filtrated was concentrated to obtain 43 mg of the title compound quantitatively as a colorless amorphous substance.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07087624B2
출처 데이터셋uspto-grants-2006_08
ORD IDord-30692bebc63d4f1ebbff40f9277d3172
출처 메모uspto-grants-2006_08