참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Nitromethane | HCID 6375 | — |
| 반응물 | 4-Bromobenzaldehyde | HCID 70741 | — |
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | trans-4-Bromo-beta-nitrostyrene | HCID 688204 | 83.8% |
반응 단계
A mixture of 4-bromobenzaldehyde (16.8 g, 91 mmol), nitromethane (24.6 mL, 455 mmol), ammonium acetate (14 g, 182 mmol), and acetic acid (160 mL) was stirred for 4 hours at 100° C. This mixture was cooled to room temperature and poured into water. The precipitate thus produced was collected, washed with water, and dried under a reduced pressure to obtain the title compound (17.4 g). The title compound was used in the following reaction without any further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08841327B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_09 |
|---|
| ORD ID | ord-047d50064f2148ab898bc3dc70987e87 |
|---|
| 출처 메모 | uspto-grants-2014_09 |
|---|
