Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 4-bromo-3-(trifluoromethyl)aniline HCl salt
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 4-Bromo-3-(trifluoromethyl)aniline | HCID 67852 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-bromo-3-(trifluoromethyl)aniline HCl salt | HCID 66745707 | 98% |
반응 단계
To a solution of 4-bromo-3-(trifluoromethyl)aniline (64 g, 267 mmol) in Et2O (500 mL) was added an HCl solution (1 M in Et2O; 300 mL) dropwise and the resulting mixture was stirred at room temp. for 16 h. The resulting pink-white precipitate was removed by filtration and washed with Et2O (50 mL) and to afford 4-bromo-3-(trifluoromethyl)aniline HCl salt (73 g, 98%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08841330B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-e7dd352353774123b85fa211e6af2f99 |
| 출처 메모 | uspto-grants-2014_09 |