Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Methoxy-5-(trifluoromethyl)aniline → 3-(4-Aminophenoxy)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Methoxy-5-(trifluoromethyl)aniline | HCID 600637 | — |
| 반응물 | Benzene, 2-isocyanato-1-methoxy-4-(trifluoromethyl)- | HCID 11983909 | — |
| 반응물 | 3-(4-Aminophenoxy)benzoic acid | HCID 23009036 | — |
| 생성물 | 3-(4-Aminophenoxy)benzoic acid | HCID 23009036 | — |
| 생성물 | N-(5-(trifluoromethyl)-2-methoxyphenyl)-N'-(3-carboxyphenyl)urea | HCID 23614600 | — |
반응 단계
Entry 36: 4-(3-Carboxyphenoxy)aniline was synthesized according to Method A11. 5-(Trifluoromethyl)-2-methoxyaniline was converted into 5-(trifluoromethyl)-2-methoxyphenyl isocyanate according to Method B1. 4-(3-Carboxyphenoxy)aniline was reacted with 5-(trifluoromethyl)-2-methoxyphenyl isocyanate according to Method C1f to afford N-(5-(trifluoromethyl)-2-methoxyphenyl)-N′-(3-carboxyphenyl)urea, which was coupled with 4-fluoroaniline according to Method D1c.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08841330B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-0d6d3c89f2ae44549d4065be26aaac3e |
| 출처 메모 | uspto-grants-2014_09 |