Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminophenol → 4-Chloro-N-methylpicolinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminophenol | HCID 403 | — |
| 반응물 | 4-Chloro-N-methylpicolinamide | HCID 1476814 | — |
| 용매 | Dimethylacetamide | HCID 31374 | — |
| 생성물 | 4-Chloro-N-methylpicolinamide | HCID 1476814 | — |
| 생성물 | 4-(4-Aminophenoxy)-N-methylpicolinamide | HCID 16655129 | — |
반응 단계
Entry 103: 4-Chloro-N-methyl-2-pyridinecarboxamide was synthesized according to Method A2, Step 3b. 4-Chloro-N-methyl-2-pyridinecarboxamide was reacted with 4-aminophenol according to Method A2, Step 4 using DMAC in place of DMF to give 4-(2-(N-methylcarbamoyl)-4-pyridyloxy)aniline. According to Method C2b, reaction of 3-amino-2-methoxyquinoline with CDI followed by 4-(2-(N-methylcarbamoyl)-4-pyridyloxy)aniline afforded bis(4-(2-(N-methylcarbamoyl)-4-pyridlyoxy)phenyl)urea.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08841330B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-2744b4db45e24ad68eba16d25b07aaea |
| 출처 메모 | uspto-grants-2014_09 |