Benzene, (2-bromoethoxy)- → 4,5-Dimethyl-3-(2-phenoxy-ethyl)-3H-thiazol-2-ylideneamine hydrobromide

참여 물질

역할	이름	HCID	투입량
반응물	Benzene, (2-bromoethoxy)-	HCID 68526	—
반응물	2-Amino-4,5-dimethyl-1,3-thiazole	HCID 73238	—
생성물	4,5-Dimethyl-3-(2-phenoxy-ethyl)-3H-thiazol-2-ylideneamine hydrobromide	HCID 68621208	50.6%

반응 조건

온도	85 °C

반응 단계

A mixture of 4,5-dimethylthiazol-2-ylamine (1.0 g, 7.8 mmol) and (2-bromo-ethoxy)benzene (1.9 g, 9.4 mmol) were heated neat to 85° C. for 19 hours. The mixture was cooled to ambient temperature and the residue was crystallized from isopropanol. The solid was collected by filtration and dried under vacuum to afford 1.3 g (50%) of the title compound. MS (DCI/NH3) m/z 249 (M+H)+.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US08841334B2
출처 데이터셋	uspto-grants-2014_09
ORD ID	ord-83cb530fe84542689d937de7db6523a9
출처 메모	uspto-grants-2014_09