2-Ethoxybenzoyl chloride → 2-Ethoxy-N-[3a-ethoxy-3-(2-methoxy-ethyl)-tetrahydro-furo[3,4-d]thiazol-2-ylidene]-benzamide

반응식

[CH2:1]([O:3][C:4]12[CH2:11][O:10][CH2:9][CH:8]1[S:7][C:6]([NH2:12])=[N:5]2)[CH3:2].[CH2:13]([O:15][C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18](Cl)=[O:19])[CH3:14]>>[CH2:13]([O:15][C:16]1[CH:24]=[CH:23][CH:22]=[CH:21][C:17]=1[C:18]([N:12]=[C:6]1[N:5]([CH2:2][CH2:1][O:3][CH3:4])[C:4]2([O:3][CH2:1][CH3:2])[CH2:11][O:10][CH2:9][CH:8]2[S:7]1)=[O:19])[CH3:14]

참가 물질

반응물 2

HCID 30163972-Ethoxybenzoyl chloride

HCID 670954813a-Ethoxy-3a,4,6,6a-tetrahydrofuro[3,4-d]thiazol-2-ylamine

생성물 1

HCID 686235912-Ethoxy-N-[3a-ethoxy-3-(2-methoxy-ethyl)-tetrahydro-furo[3,4-d]thiazol-2-ylidene]-benzamide

실험 절차

The product from Example 125B and 2-ethoxybenzoyl chloride were processed as described for example 118A to afford the title compound. MS (ESI+) m/z 395 (M+H)+.

출처 및 근거

ORD 기록: ord-84d87c592b8a4e1a946e58405e41dde9
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08841334B2

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