Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Quinolinecarboxylic acid → 4-Quinolinecarbonyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Quinolinecarboxylic acid | HCID 10243 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | 4-Quinolinecarbonyl chloride | HCID 9990126 | — |
반응 단계
A solution of 4-quinolinecarboxylic acid (Aldrich, 0.25 g, 1.4 mmol) in 5 mL of thionyl chloride was warmed to reflux and allowed to stir for 1 hour. The mixture was then cooled to ambient temperature and concentrated under reduced pressure. This material was dissolved in 10 mL toluene and concentrated under reduced pressure (3×) to afford the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08841334B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-cdafd995a22746e6b7c3dd5a072b0f2f |
| 출처 메모 | uspto-grants-2014_09 |