2-Bromoethyl methyl ether → 5-Tert-butyl-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromide

반응식

[C:1]([C:5]1[S:9][C:8]([NH2:10])=[N:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[CH3:11][O:12][CH2:13][CH2:14][Br:15]>>[BrH:15].[C:1]([C:5]1[S:9][C:8](=[NH:10])[N:7]([CH2:14][CH2:13][O:12][CH3:11])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 809722-Bromoethyl methyl ether

HCID 6764855-tert-Butyl-1,3-thiazol-2-amine

생성물 1

HCID 668591825-Tert-butyl-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromide

실험 절차

A mixture of Example 202A and commercially available 2-bromoethyl methyl ether (Aldrich) were processed according to the method described in Example 12A to afford the title compound. MS (ESI+) m/z 215 (M+H)+.

출처 및 근거

ORD 기록: ord-7f97a660387e4324930451b76fdb850b
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08841334B2

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