Furan, 2-(bromomethyl)tetrahydro- → 5-propyl-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-imine

반응식

[CH2:1]([C:4]1[S:8][C:7]([NH2:9])=[N:6][CH:5]=1)[CH2:2][CH3:3].Br[CH2:11][CH:12]1[CH2:16][CH2:15][CH2:14][O:13]1>>[CH2:1]([C:4]1[S:8][C:7](=[NH:9])[N:6]([CH2:11][CH:12]2[CH2:16][CH2:15][CH2:14][O:13]2)[CH:5]=1)[CH2:2][CH3:3]

참가 물질

반응물 2

HCID 14501Furan, 2-(bromomethyl)tetrahydro-

HCID 32822365-Propyl-1,3-thiazol-2-amine

생성물 1

HCID 686240445-propyl-3-((tetrahydrofuran-2-yl)methyl)thiazol-2(3H)-imine

실험 절차

A mixture of 5-propylthiazol-2-amine and 2-(bromomethyl)tetrahydrofuran were processed using the method described in Example 2A to afford the title compound. MS (ESI) m/z 227 (M+H)+.

출처 및 근거

ORD 기록: ord-7508b042c19d49a6a9808d0727fbf4f8
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08841334B2

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