Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → Methyl 3-Amino-6-bromopyrazine-2-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | Methyl 3-aminopyrazinecarboxylate | HCID 72669 | — |
| 용매 | Acetonitrile | HCID 6342 | — |
| 생성물 | Methyl 3-Amino-6-bromopyrazine-2-carboxylate | HCID 227251 | 92.3% |
반응 단계
A mixture of methyl 3-aminopyrazine-2-carboxylate (8.35 g, 54.53 mmol) and N-bromo-succinimide (9.705 g, 54.53 mmol) was stirred in MeCN (100 mL) at room temp overnight. The resultant precipitate was filtered, washed with MeCN and dried to give the desired product as a yellow solid (11.68 g, 92% Yield)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08841308B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-9c45557af7b8499583d6e81ed74ae82b |
| 출처 메모 | uspto-grants-2014_09 |