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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 78797생성일: 2026년 10월 25일

1-(3-Aminopropyl)-2-pyrrolidinone → 3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamide

https://huagongshe.com/reaction/78797

반응식

참여 물질

역할이름HCID투입량
반응물1-(3-Aminopropyl)-2-pyrrolidinoneHCID 82111—
반응물3-((2-Fluoro-4-iodophenyl)amino)isonicotinic acidHCID 59026791—
생성물3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamideHCID 11648689—

반응 단계

3-[(2-fluoro-4-iodophenyl)amino]-N-[3-(2-oxopyrrolidin-1-yl)propyl]isonicotinamide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.6 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.85 mmol of 1-(3-amino-propyl)-pyrrolidin-2-one LC/MS [8.70 min; 483 (M+1)].

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08841459B2
출처 데이터셋uspto-grants-2014_09
ORD IDord-806cb2c300634d04bb6f023661f7b0f1
출처 메모uspto-grants-2014_09