m-Anisohydrazide → 3-[(2-fluoro-4-iodophenyl)amino]-N'-(3-methoxybenzoyl)isonicotinohydrazide

HRID 78819

반응식

HRID 78819 반응식
[F:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12]([OH:14])=O.[CH3:19][O:20][C:21]1[CH:22]=[C:23]([CH:28]=[CH:29][CH:30]=1)[C:24]([NH:26][NH2:27])=[O:25]>>[F:1][C:2]1[CH:7]=[C:6]([I:8])[CH:5]=[CH:4][C:3]=1[NH:9][C:10]1[CH:18]=[N:17][CH:16]=[CH:15][C:11]=1[C:12]([NH:27][NH:26][C:24](=[O:25])[C:23]1[CH:28]=[CH:29][CH:30]=[C:21]([O:20][CH3:19])[CH:22]=1)=[O:14]

참가 물질

3

반응물 2

HCID 79848m-AnisohydrazideHCID 590267913-((2-Fluoro-4-iodophenyl)amino)isonicotinic acid2회

생성물 1

HCID 115770373-[(2-fluoro-4-iodophenyl)amino]-N'-(3-methoxybenzoyl)isonicotinohydrazide

실험 절차

3-[(2-fluoro-4-iodophenyl)amino]-N′-(3-methoxybenzoyl)isonicotinohydrazide was synthesized according to the procedure for General Method 1, outlined above, starting with 0.4 mmol of 3-[(2-fluoro-4-iodophenyl)amino]isonicotinic acid (intermediate 1) and 0.55 mmol of 3-methoxy-benzohydrazide. LC/MS [9.23 min; 507 (M+1)]

후처리

  1. customLC/MS [9.23 min; 507 (M+1)]

출처 및 근거

ORD 기록
ord-51108bab6bd04c59aae1e7663aedc680
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08841459B2

연결된 노트

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