1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) → 9-Cyclopentyl-2-((5-((3R)-3-(tert-butyldimethylsilyloxy)pyrrolidin-1-yl)-2-pyridinyl)amino)-8-methyl-8,9-dihydro-7H-pyrido[3',2':4,5]pyrrolo[2,3-d]-pyrimidin-7-one

반응식

[NH2:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]3[CH:11]=[CH:12][C:13](=[O:16])[N:14]([CH3:15])[C:9]=3[N:8]([CH:17]3[CH2:21][CH2:20][CH2:19][CH2:18]3)[C:6]=2[N:7]=1.[Si:22]([O:29][C@@H:30]1[CH2:34][CH2:33][N:32]([C:35]2[CH:36]=[CH:37][C:38](Cl)=[N:39][CH:40]=2)[CH2:31]1)([C:25]([CH3:28])([CH3:27])[CH3:26])([CH3:24])[CH3:23].C1(P(C2C=CC=CC=2)C2C3OC4C(=CC=CC=4P(C4C=CC=CC=4)C4C=CC=CC=4)C(C)(C)C=3C=CC=2)C=CC=CC=1.CC(C)([O-])C.[Na+]>O1CCOCC1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.C1C=CC(/C=C/C(/C=C/C2C=CC=CC=2)=O)=CC=1.[Pd].[Pd]>[CH:17]1([N:8]2[C:6]3[N:7]=[C:2]([NH:1][C:38]4[CH:37]=[CH:36][C:35]([N:32]5[CH2:33][CH2:34][C@@H:30]([O:29][Si:22]([C:25]([CH3:28])([CH3:27])[CH3:26])([CH3:23])[CH3:24])[CH2:31]5)=[CH:40][N:39]=4)[N:3]=[CH:4][C:5]=3[C:10]3[CH:11]=[CH:12][C:13](=[O:16])[N:14]([CH3:15])[C:9]2=3)[CH2:18][CH2:19][CH2:20][CH2:21]1