Hydrazine → HCID 67259880, 화합물
반응식
[Br:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[N+:11]([O-:13])=[O:12])[N:4]([CH2:14][C:15]([O:17]CC)=O)[N:3]=1.[NH2:20][NH2:21]>CCO>[Br:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[N+:11]([O-:13])=[O:12])[N:4]([CH2:14][C:15]([NH:20][NH2:21])=[O:17])[N:3]=1참가 물질
4
실험 절차
A solution of ethyl 2-(3-bromo-4-nitro-1H-indazol-1-yl)acetate (1.48 g, 4.51 mmol) in absolute EtOH (20 mL) was treated at ambient temperature with hydrazine (1.45 g, 45.1 mmol) and was heated at reflux for 16 hours under a nitrogen atmosphere. The reaction mixture was cooled to ambient temperature, and the precipitate was isolated by filtration. The solids were dried under vacuum to afford the product (0.865 g) as a tan powder.
후처리
- temperaturewas heated
- temperatureat reflux for 16 hours under a nitrogen atmosphere
- customthe precipitate was isolated by filtration
- customThe solids were dried under vacuum
출처 및 근거
- ORD 기록
- ord-bf8e3b566e07458aba1ab44cd33fab30
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08841455B2
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